Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 10/20 | 0.43 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.43 |
| ▸ | EDNRB | P24530 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL534996 | 0.94 | EDNRA (0.43) | EDNRAAGTR1EDNRB | |
| SCHEMBL30844562 | 0.91 | EDNRA (0.41) | EDNRAAGTR1EDNRB | |
| SCHEMBL30757327 | 0.90 | EDNRA (0.43) | EDNRAAGTR1EDNRB | |
| SCHEMBL4291679 | 0.90 | EDNRA (0.43) | EDNRAAGTR1EDNRB | |
| SCHEMBL26688766 | 0.90 | EDNRA (0.43) | EDNRAAGTR1EDNRB | |
| SCHEMBL30757240 | 0.90 | EDNRA (0.43) | EDNRAAGTR1EDNRB | |
| SCHEMBL535104 | 0.90 | EDNRA (0.43) | EDNRAAGTR1EDNRB | |
| SCHEMBL30296110 | 0.89 | EDNRA (0.40) | EDNRAAGTR1EDNRB | |
| SCHEMBL5531210 | 0.87 | EDNRA (0.41) | EDNRAAGTR1EDNRB | |
| SCHEMBL30171097 | 0.87 | EDNRA (0.41) | EDNRAAGTR1EDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117836294-A | Biological antagonist containing aromatic ring, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2024-04-05 | — | — | CN | disclosed |