SCHEMBL30845347

SCHEMBL30845347

O=C(CCc1ccc(Cl)cc1)N[C@H](Cc1ccc(O)cc1)C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
NAALAD2 Q9Y3Q0 1/20 0.54
NHERF1 O14745 1/20 0.54
ACE P12821 3/20 0.53
KMT2A Q03164 2/20 0.52
FOLH1 Q04609 1/20 0.51
ITGB3 P05106 1/20 0.51
ITGA2B P08514 1/20 0.51
GPR34 Q9UPC5 1/20 0.51
GRIA1 P42261 1/20 0.50
MEN1 O00255 1/20 0.50
CA2 P00918 2/20 0.49
CA1 P00915 1/20 0.49
MME P08473 1/20 0.48
CCKBR P32239 1/20 0.48
ITGB1 P05556 1/20 0.47
ITGA4 P13612 1/20 0.47
ITGB7 P26010 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4147882 0.93 NAALAD2 (0.61) NAALAD2ACEFOLH1ITGB3ITGA2B
SCHEMBL4147877 0.93 NAALAD2 (0.61) NAALAD2ACEFOLH1ITGB3ITGA2B
SCHEMBL4147924 0.89 ITGB3 (0.62) NAALAD2ACEFOLH1ITGB3ITGA2B
SCHEMBL4147413 0.89 ITGB3 (0.62) NAALAD2ACEFOLH1ITGB3ITGA2B
SCHEMBL4147417 0.89 ITGB3 (0.62) NAALAD2ACEFOLH1ITGB3ITGA2B
SCHEMBL4147927 0.89 ITGB3 (0.62) NAALAD2ACEFOLH1ITGB3ITGA2B
SCHEMBL31006610 0.88 KMT2A (0.51) ACEKMT2AITGB3ITGA2BGPR34
SCHEMBL31006620 0.88 GPR34 (0.61) ACEKMT2AITGB3ITGA2BGPR34
SCHEMBL30081065 0.86 ACE (0.56) NAALAD2ACEFOLH1ITGB3ITGA2B
SCHEMBL30081063 0.86 ACE (0.56) NAALAD2ACEFOLH1ITGB3ITGA2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117616034-A Composition for preventing or treating inflammatory bowel disease containing novel compounds 安尼根有限公司 2024-02-27 CN disclosed