Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 5/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.46 |
| ▸ | MET | P08581 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.46 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.46 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.46 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.46 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.42 |
| ▸ | SYK | P43405 | 2/20 | 0.42 |
| ▸ | AURKA | O14965 | 1/20 | 0.42 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.42 |
| ▸ | FLT3 | P36888 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29560146 | 0.84 | IRAK4 (0.46) | IRAK4KDM4ELIMK1ALDH1A1IRAK1 | |
| SCHEMBL17023631 | 0.82 | IRAK4 (0.49) | IRAK4KDM4ELIMK1ALDH1A1L3MBTL1 | |
| SCHEMBL29560247 | 0.80 | KDM4E (0.48) | IRAK4KDM4ETDP1LIMK1ALDH1A1 | |
| SCHEMBL7114666 | 0.80 | KDM4E (0.48) | IRAK4KDM4ETDP1LIMK1ALDH1A1 | |
| SCHEMBL30844941 | 0.79 | PARP1 (0.53) | IRAK4KDM4ELIMK1ALDH1A1L3MBTL1 | |
| SCHEMBL19555042 | 0.79 | PARP1 (0.53) | IRAK4KDM4ELIMK1ALDH1A1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL30845090 | 0.78 | PARP1 (0.51) | IRAK4KDM4ELIMK1ALDH1A1L3MBTL1 | |
| SCHEMBL29559995 | 0.77 | IRAK4 (0.51) | IRAK4ALDH1A1IRAK1SYKAURKA | |
| SCHEMBL15466759 | 0.76 | ALDH1A1 (0.46) | KDM4ETDP1PSMD14ALDH1A1POLB | |
| Water SCHEMBL30682486 | 0.76 | IRAK4 (0.50) | IRAK4ALDH1A1IRAK1SYKAURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113423711-B | Thieno [3,2-B ] pyridine derivatives as UDP glycosyltransferase inhibitors and methods of use thereof | 建新公司 | 2024-03-15 | — | — | CN | disclosed |