Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.53 |
| ▸ | LIMK1 | P53667 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | IRAK4 | Q9NWZ3 | 4/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PLK4 | O00444 | 1/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | ROS1 | P08922 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | AXL | P30530 | 1/20 | 0.40 |
| ▸ | FLT3 | P36888 | 1/20 | 0.40 |
| ▸ | FRK | P42685 | 1/20 | 0.40 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.40 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.40 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.40 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.40 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.40 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.40 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19555042 | 1.00 | PARP1 (0.53) | PARP1LIMK1KDM4EIRAK4L3MBTL1 | |
| Hydrochloric Acid SCHEMBL30845090 | 0.98 | PARP1 (0.51) | PARP1LIMK1KDM4EIRAK4L3MBTL1 | |
| Trifluoroacetic Acid SCHEMBL30844916 | 0.90 | L3MBTL1 (0.50) | PARP1LIMK1KDM4EIRAK4L3MBTL1 | |
| SCHEMBL7114666 | 0.84 | KDM4E (0.48) | LIMK1KDM4EIRAK4L3MBTL1IRAK1 | |
| SCHEMBL29560247 | 0.84 | KDM4E (0.48) | LIMK1KDM4EIRAK4L3MBTL1IRAK1 | |
| SCHEMBL17023631 | 0.83 | IRAK4 (0.49) | PARP1LIMK1KDM4EIRAK4L3MBTL1 | |
| SCHEMBL8555310 | 0.82 | IRAK4 (0.44) | PARP1LIMK1KDM4EIRAK4L3MBTL1 | |
| SCHEMBL30845404 | 0.79 | IRAK4 (0.55) | LIMK1KDM4EIRAK4L3MBTL1FLT3 | |
| SCHEMBL3385296 | 0.76 | LIMK1 (0.44) | PARP1LIMK1KDM4EIRAK4L3MBTL1 | |
| SCHEMBL29560146 | 0.75 | IRAK4 (0.46) | LIMK1KDM4EIRAK4FLT3IRAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113423711-B | Thieno [3,2-B ] pyridine derivatives as UDP glycosyltransferase inhibitors and methods of use thereof | 建新公司 | 2024-03-15 | — | — | CN | claimed |
| CN-118239963-A | Compounds as eIF4E inhibitors and uses thereof | 南京圣和药业股份有限公司 | 2024-06-25 | — | — | CN | disclosed |
| CN-113423711-B | Thieno [3,2-B ] pyridine derivatives as UDP glycosyltransferase inhibitors and methods of use thereof | 建新公司 | 2024-03-15 | — | — | CN | disclosed |