Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 18/20 | 1.00 |
| ▸ | CSF1R | P07333 | 15/20 | 0.76 |
| ▸ | KDR | P35968 | 3/20 | 0.74 |
| ▸ | RET | P07949 | 1/20 | 0.74 |
| ▸ | KIF5B | P33176 | 1/20 | 0.74 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.73 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.73 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | GAK | O14976 | 1/20 | 0.55 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.55 |
| ▸ | ABL1 | P00519 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CDK1 | P06493 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | FBP1 | P09467 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | SRC | P12931 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2257706 | 0.85 | CSF1R (1.00) | EGFRCSF1RKDRRETKIF5B | |
| SCHEMBL6181700 | 0.85 | EGFR (1.00) | EGFRCSF1RKDRRETKIF5B | |
| Hydrochloric Acid SCHEMBL6179746 | 0.84 | CSF1R (1.00) | EGFRCSF1RKDRRETKIF5B | |
| Hydrochloric Acid SCHEMBL6180093 | 0.84 | EGFR (1.00) | EGFRCSF1RKDRRETKIF5B | |
| SCHEMBL27662120 | 0.82 | EGFR (0.70) | EGFRCSF1RKDRRETKIF5B | |
| SCHEMBL6181635 | 0.82 | EGFR (1.00) | EGFRCSF1RKDRRETKIF5B | |
| SCHEMBL27641671 | 0.82 | EGFR (0.69) | EGFRCSF1RKDRRETKIF5B | |
| Hydrochloric Acid SCHEMBL6180417 | 0.81 | EGFR (1.00) | EGFRCSF1RKDRRETKIF5B | |
| SCHEMBL6836525 | 0.80 | EGFR (0.67) | EGFRCSF1RKDRRETKIF5B | |
| SCHEMBL6183306 | 0.79 | CSF1R (1.00) | EGFRCSF1RKDRRETKIF5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4578457-A1 | PHARMACEUTICAL FOR TREATING AND/OR PREVENTING CANCER | Toray Industries, Inc. (JP) | 2025-07-02 | — | — | EP | disclosed |
| CN-119768182-A | Medicine for treating and/or preventing cancer | 东丽株式会社 | 2025-04-04 | — | — | CN | disclosed |
| WO-2024178274-A2 | METHODS OF DEGRADING RAF(RAF) PROTEIN IN CELLS USING MITOGEN-ACTIVATED PROTEIN KINASE KINASE 1/2 (MEK1/2) PROTEIN DEGRADERS | INSTITUTE FOR CANCER RESEARCH D/B/A THE RESEARCH INSTITUTE OF FOX CHASE CANCER CENTER (US) | 2024-08-29 | — | — | WO | disclosed |
| WO-2024043252-A1 | PHARMACEUTICAL FOR TREATING AND/OR PREVENTING CANCER | 東レ株式会社 | 2024-02-29 | — | — | WO | disclosed |