SCHEMBL30846558

SCHEMBL30846558

Clc1nc(Cc2ccccc2)c2[nH]cnc2n1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDE4A P27815 1/20 0.50
PDE4B Q07343 1/20 0.50
PDE4C Q08493 1/20 0.50
PDE4D Q08499 1/20 0.50
TMIGD3 P0DMS9 1/20 0.49
HTR2C P28335 1/20 0.49
HTR2B P41595 1/20 0.49
XDH P47989 1/20 0.49
SMN1; SMN2 Q16637 2/20 0.46
CDK1 P06493 3/20 0.45
PIN1 Q13526 2/20 0.45
CYP1A2 P05177 2/20 0.45
CYP3A4 P08684 2/20 0.45
CYP2D6 P10635 2/20 0.45
CYP2C9 P11712 2/20 0.45
CCNB1 P14635 2/20 0.45
CCNA2 P20248 2/20 0.45
CDK2 P24941 2/20 0.45
CYP2C19 P33261 2/20 0.45
CCNA1 P78396 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL72543 0.82 CDK2 (0.62) PDE4APDE4BPDE4CPDE4DSMN1; SMN2
SCHEMBL1081386 0.82 PDE4A (0.50) PDE4APDE4BPDE4CPDE4DCDK1
Hydrochloric Acid SCHEMBL27818634 0.81 CDK2 (0.60) PDE4APDE4BPDE4CPDE4DSMN1; SMN2
SCHEMBL27886988 0.81 CDK2 (0.60) PDE4APDE4BPDE4CPDE4DSMN1; SMN2
SCHEMBL31620288 0.80 SMN1; SMN2 (0.64) TMIGD3HTR2CHTR2BXDHSMN1; SMN2
Ammonia Solution, Strong SCHEMBL28783311 0.78 CDC7 (0.57) PDE4APDE4BPDE4CPDE4DSMN1; SMN2
SCHEMBL7437649 0.77 PIN1 (0.71) TMIGD3HTR2CHTR2BCDK1PIN1
SCHEMBL5384434 0.76 CDC7 (0.59) PDE4APDE4BPDE4CPDE4DSMN1; SMN2
Alcohol SCHEMBL27857990 0.76 PIN1 (0.55) PDE4APDE4BPDE4CPDE4DSMN1; SMN2
SCHEMBL16146535 0.76 XDH (0.56) TMIGD3HTR2CHTR2BXDHSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119912510-A Modulators of extracellular 5' -nucleotidases and uses thereof 艾库斯生物科学有限公司 2025-05-02 CN disclosed
CN-114395005-B Modulators of extracellular 5' -nucleotidases and uses thereof 艾库斯生物科学有限公司 2024-12-31 CN disclosed
CN-108697719-B Modulators of extracellular 5' -nucleotidases and uses thereof 艾库斯生物科学有限公司 2024-03-19 CN disclosed