Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 11/20 | 0.81 |
| ▸ | MAOA | P21397 | 10/20 | 0.81 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.51 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.51 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA3 | P07451 | 1/20 | 0.39 |
| ▸ | CA6 | P23280 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23295265 | 0.92 | MAOA (0.96) | MAOBMAOADDB1CRBNAR | |
| SCHEMBL2578708 | 0.90 | MAOA (1.00) | MAOBMAOADDB1CRBNAR | |
| SCHEMBL31061343 | 0.88 | MAOA (0.71) | MAOBMAOADDB1CRBNAR | |
| SCHEMBL15231515 | 0.87 | MAOB (0.69) | MAOBMAOADDB1CRBNAR | |
| SCHEMBL21887035 | 0.81 | MAOA (0.62) | MAOBMAOADDB1CRBNHRH3 | |
| SCHEMBL21887036 | 0.77 | MAOA (0.57) | MAOBMAOADDB1CRBNHRH3 | |
| SCHEMBL2578637 | 0.75 | MAOA (0.62) | MAOBMAOADDB1CRBNAR | |
| SCHEMBL21824778 | 0.73 | MAOA (0.51) | MAOBMAOADDB1CRBNALDH1A1 | |
| SCHEMBL21825012 | 0.73 | MAOA (0.51) | MAOBMAOADDB1CRBNALDH1A1 | |
| SCHEMBL1746402 | 0.71 | MAOA (0.46) | MAOBMAOAALDH1A1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117843633-A | Sulfoximine compounds, pharmaceutical compositions and uses thereof | 上海海和药物研究开发股份有限公司 | 2024-04-09 | — | — | CN | disclosed |