Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLQ | O75417 | 4/20 | 0.38 |
| ▸ | TACR1 | P25103 | 4/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30847735 | 1.00 | POLQ (0.38) | POLQTACR1P2RX7DRD2DRD3 | |
| SCHEMBL30847713 | 0.89 | POLQ (0.41) | POLQTACR1P2RX7DRD2DRD3 | |
| SCHEMBL30847546 | 0.88 | POLQ (0.37) | POLQ | |
| SCHEMBL30847786 | 0.86 | POLQ (0.39) | POLQTACR1P2RX7 | |
| SCHEMBL30847772 | 0.86 | POLQ (0.38) | POLQTACR1P2RX7DRD2DRD3 | |
| SCHEMBL30847774 | 0.85 | POLQ (0.41) | POLQTACR1P2RX7 | |
| SCHEMBL30847767 | 0.84 | POLQ (0.39) | POLQTACR1DRD2DRD3 | |
| SCHEMBL30847627 | 0.84 | POLQ (0.38) | POLQP2RX7 | |
| SCHEMBL30847678 | 0.84 | POLQ (0.43) | POLQP2RX7DRD2DRD3 | |
| SCHEMBL30847683 | 0.83 | POLQ (0.38) | POLQTACR1P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4598901-A1 | PYRROLIDINE AND IMIDAZOLIDINE BASED DNA POLYMERASE THETA INHIBITORS AND USE THEREOF | Thomas Jefferson University (US) | 2025-08-13 | — | — | EP | disclosed |
| WO-2024076964-A1 | PYRROLIDINE AND IMIDAZOLIDINE BASED DNA POLYMERASE THETA INHIBITORS AND USE THEREOF | THOMAS JEFFERSON UNIVERSITY (US) | 2024-04-11 | — | — | WO | disclosed |