Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC40A1 | Q9NP59 | 12/20 | 0.46 |
| ▸ | CLK1 | P49759 | 1/20 | 0.41 |
| ▸ | EIF2AK3 | Q9NZJ5 | 1/20 | 0.38 |
| ▸ | NFKBIA | P25963 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CCR9 | P51686 | 1/20 | 0.37 |
| ▸ | OXTR | P30559 | 2/20 | 0.37 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.37 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27132418 | 1.00 | SLC40A1 (0.46) | SLC40A1CLK1EIF2AK3NFKBIARELA | |
| SCHEMBL30847889 | 1.00 | SLC40A1 (0.46) | SLC40A1CLK1EIF2AK3NFKBIARELA | |
| SCHEMBL27139762 | 0.94 | SLC40A1 (0.39) | SLC40A1CLK1GLO1 | |
| SCHEMBL27142237 | 0.94 | SLC40A1 (0.39) | SLC40A1CLK1KMT2AGLO1 | |
| SCHEMBL27134065 | 0.92 | GLO1 (0.44) | SLC40A1NFKBIAKMT2ACCR9GLO1 | |
| SCHEMBL30847924 | 0.92 | GLO1 (0.44) | SLC40A1NFKBIAKMT2ACCR9GLO1 | |
| SCHEMBL27133365 | 0.91 | SLC40A1 (0.40) | SLC40A1CLK1EIF2AK3KMT2AGLO1 | |
| SCHEMBL27142031 | 0.90 | SLC40A1 (0.37) | SLC40A1CLK1TSHRKMT2AOXTR | |
| SCHEMBL30847920 | 0.90 | GLO1 (0.40) | SLC40A1NFKBIAKMT2AGLO1 | |
| SCHEMBL27133987 | 0.90 | GLO1 (0.40) | SLC40A1NFKBIAKMT2AGLO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4577536-A1 | PYRAZOLYLSULFONAMIDE COMPOUNDS AND THEIR USE IN THERAPY | Hotspot Therapeutics, Inc. (US) | 2025-07-02 | — | — | EP | disclosed |
| WO-2024044730-A1 | PYRAZOLYLSULFONAMIDE COMPOUNDS AND THEIR USE IN THERAPY | HOTSPOT THERAPEUTICS, INC. (US) | 2024-02-29 | — | — | WO | disclosed |