Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29172083 | 1.00 | CYP11B1 (0.38) | CYP11B1CYP11B2MEN1KMT2ATRPV4 | |
| SCHEMBL23834717 | 0.76 | KMT2A (0.36) | MEN1KMT2A | |
| SCHEMBL29921092 | 0.76 | KMT2A (0.36) | MEN1KMT2A | |
| SCHEMBL30848245 | 0.76 | KDM4E (0.30) | — | |
| SCHEMBL30848118 | 0.76 | TTR (0.42) | — | |
| SCHEMBL29172038 | 0.76 | KDM4E (0.30) | — | |
| SCHEMBL29171967 | 0.76 | TTR (0.42) | — | |
| SCHEMBL30848072 | 0.74 | HTT (0.39) | CYP11B2MEN1KMT2A | |
| SCHEMBL29172088 | 0.74 | HTT (0.39) | CYP11B2MEN1KMT2A | |
| SCHEMBL25237207 | 0.72 | TRPV4 (0.36) | CYP11B1CYP11B2MEN1KMT2ATRPV4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117720472-A | Benzimidazole compound, and preparation method and application thereof | 苏州沪云新药研发股份有限公司 | 2024-03-19 | — | — | CN | disclosed |