Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.39 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.39 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.35 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.30 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.30 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.30 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
| ▸ | MYC | P01106 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29172088 | 1.00 | HTT (0.39) | HTTTSHRAPOBEC3AAPOBEC3GNCOA1 | |
| SCHEMBL29171967 | 0.86 | TTR (0.42) | HTTALDH1A1LMNA | |
| SCHEMBL30848118 | 0.86 | TTR (0.42) | HTTALDH1A1LMNA | |
| SCHEMBL30848096 | 0.82 | MAPT (0.32) | HTTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL29171976 | 0.82 | KMT2A (0.39) | ALDH1A1SMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL30848134 | 0.76 | TSHR (0.41) | HTTTSHRAPOBEC3AAPOBEC3GNCOA1 | |
| SCHEMBL29171955 | 0.76 | TSHR (0.41) | HTTTSHRAPOBEC3AAPOBEC3GNCOA1 | |
| SCHEMBL29171893 | 0.76 | TTR (0.42) | HTTTSHRAPOBEC3AAPOBEC3GNCOA1 | |
| SCHEMBL30848003 | 0.74 | CYP11B1 (0.38) | MEN1KMT2ACYP11B2 | |
| SCHEMBL29172083 | 0.74 | CYP11B1 (0.38) | MEN1KMT2ACYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117720472-A | Benzimidazole compound, and preparation method and application thereof | 苏州沪云新药研发股份有限公司 | 2024-03-19 | — | — | CN | disclosed |