Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30848118 | 0.84 | TTR (0.42) | HPGDALDH1A1LMNAHTT | |
| SCHEMBL29171967 | 0.84 | TTR (0.42) | HPGDALDH1A1LMNAHTT | |
| SCHEMBL30848072 | 0.82 | HTT (0.39) | ALDH1A1LMNAHTTMEN1KMT2A | |
| SCHEMBL29172088 | 0.82 | HTT (0.39) | ALDH1A1LMNAHTTMEN1KMT2A | |
| SCHEMBL29171976 | 0.80 | KMT2A (0.39) | MAPTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL30798713 | 0.79 | TTR (0.39) | MAPTHPGDALDH1A1MEN1KMT2A | |
| SCHEMBL30848416 | 0.78 | ERN1 (0.34) | HPGDALDH1A1HTTKMT2A | |
| SCHEMBL30848324 | 0.75 | AR (0.34) | MAPTHPGDALDH1A1 | |
| SCHEMBL30848332 | 0.74 | MAPT (0.34) | MAPTHPGD | |
| SCHEMBL29172083 | 0.72 | CYP11B1 (0.38) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117720472-A | Benzimidazole compound, and preparation method and application thereof | 苏州沪云新药研发股份有限公司 | 2024-03-19 | — | — | CN | disclosed |