Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.30 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.30 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.30 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30848412 | 0.84 | TTR (0.42) | HPGDARL3MBTL1ABCC9ABCC8 | |
| SCHEMBL29172058 | 0.84 | TTR (0.42) | HPGDARL3MBTL1ABCC9ABCC8 | |
| SCHEMBL30848234 | 0.82 | TSHR (0.39) | L3MBTL1ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL29171913 | 0.82 | TSHR (0.39) | L3MBTL1ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL29172030 | 0.80 | NOTUM (0.41) | MAPTARL3MBTL1 | |
| SCHEMBL30798713 | 0.79 | TTR (0.39) | MAPTHPGD | |
| SCHEMBL30848213 | 0.78 | ERN1 (0.34) | HPGDL3MBTL1 | |
| SCHEMBL30848324 | 0.75 | AR (0.34) | MAPTHPGDARCTSK | |
| SCHEMBL30848096 | 0.74 | MAPT (0.32) | MAPTHPGD | |
| SCHEMBL30848145 | 0.72 | AR (0.34) | ARL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117720472-A | Benzimidazole compound, and preparation method and application thereof | 苏州沪云新药研发股份有限公司 | 2024-03-19 | — | — | CN | disclosed |