Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 2/20 | 0.46 |
| ▸ | TPMT | P51580 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA7 | P43166 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CA3 | P07451 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SELL | P14151 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SELP | P16109 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29172054 | 1.00 | TTR (0.46) | TTRTPMTLMNAMAPK1HTT | |
| SCHEMBL29171886 | 0.85 | HTT (0.41) | LMNAHTTKDM4EALDH1A1MAPT | |
| SCHEMBL30848020 | 0.85 | HTT (0.41) | LMNAHTTKDM4EALDH1A1MAPT | |
| SCHEMBL30848213 | 0.82 | ERN1 (0.34) | HTTALDH1A1HPGDSMN1; SMN2HDAC1 | |
| SCHEMBL29171871 | 0.82 | NOTUM (0.48) | LMNARAB9ACA12CA1CA2 | |
| SCHEMBL14703661 | 0.77 | MAPK1 (0.44) | TTRTPMTLMNAMAPK1HTT | |
| SCHEMBL9478920 | 0.77 | TTR (0.56) | TTRTPMTLMNAMAPK1CA12 | |
| SCHEMBL29172074 | 0.76 | KMT2A (0.40) | HTTALDH1A1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL29172058 | 0.76 | TTR (0.42) | TTRTPMTLMNAALDH1A1HPGD | |
| SCHEMBL14958073 | 0.74 | MYC (0.31) | CA2ALDH1A1SELLSELPSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117720472-A | Benzimidazole compound, and preparation method and application thereof | 苏州沪云新药研发股份有限公司 | 2024-03-19 | — | — | CN | disclosed |