Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.41 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.39 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.37 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 2/20 | 0.33 |
| ▸ | STING1 | Q86WV6 | 2/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.33 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.32 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | BTK | Q06187 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30848020 | 1.00 | HTT (0.41) | HTTTSHRAPOBEC3AAPOBEC3GDGAT1 | |
| SCHEMBL29172054 | 0.85 | TTR (0.46) | HTTALDH1A1KMT2ASMN1; SMN2HDAC1 | |
| SCHEMBL30848187 | 0.85 | TTR (0.46) | HTTALDH1A1KMT2ASMN1; SMN2HDAC1 | |
| SCHEMBL29171871 | 0.81 | NOTUM (0.48) | ALDH1A1PTPN11KDM4ELMNAPOLB | |
| SCHEMBL30848213 | 0.81 | ERN1 (0.34) | HTTALDH1A1KMT2ASMN1; SMN2HDAC1 | |
| SCHEMBL19117750 | 0.78 | PARP1 (0.39) | HTTTSHRAPOBEC3AAPOBEC3GSMN1; SMN2 | |
| SCHEMBL30848234 | 0.76 | TSHR (0.39) | HTTTSHRAPOBEC3AAPOBEC3GNCOA1 | |
| SCHEMBL29171913 | 0.76 | TSHR (0.39) | HTTTSHRAPOBEC3AAPOBEC3GNCOA1 | |
| SCHEMBL29172074 | 0.74 | KMT2A (0.40) | HTTTSHRALDH1A1MEN1KMT2A | |
| SCHEMBL15020381 | 0.74 | CES2 (0.46) | HTTTSHRAPOBEC3AAPOBEC3GDGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117720472-A | Benzimidazole compound, and preparation method and application thereof | 苏州沪云新药研发股份有限公司 | 2024-03-19 | — | — | CN | disclosed |