Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 3/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | RXRB | P28702 | 1/20 | 0.36 |
| ▸ | RXRG | P48443 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ATR | Q13535 | 1/20 | 0.31 |
| ▸ | PARG | Q86W56 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29384146 | 0.87 | CYP4F2 (0.39) | CYP4F2CYP4A11RXRARXRBRXRG | |
| SCHEMBL16647245 | 0.87 | CYP4F2 (0.39) | CYP4F2CYP4A11RXRARXRBRXRG | |
| SCHEMBL19096200 | 0.83 | RXRA (0.35) | CYP4F2CYP4A11RXRARXRBRXRG | |
| SCHEMBL30641330 | 0.81 | RXRA (0.38) | CYP4F2CYP4A11RXRARXRBRXRG | |
| SCHEMBL26674786 | 0.81 | RXRA (0.38) | CYP4F2CYP4A11RXRARXRBRXRG | |
| SCHEMBL21230708 | 0.76 | CYP4F2 (0.46) | CYP4F2CYP4A11RXRARXRBRXRG | |
| SCHEMBL29478948 | 0.76 | RXRA (0.38) | CYP4F2CYP4A11RXRARXRBRXRG | |
| SCHEMBL21393943 | 0.76 | RXRA (0.38) | CYP4F2CYP4A11RXRARXRBRXRG | |
| SCHEMBL25795327 | 0.74 | RXRA (0.40) | CYP4F2CYP4A11RXRARXRBRXRG | |
| SCHEMBL23043733 | 0.74 | CYP4F2 (0.39) | CYP4F2CYP4A11RXRARXRBRXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024064335-A1 | NAPHTHYL-SUBSTITUTED PYRANOPYRIMIDINONES AND RELATED COMPOUNDS AND THEIR USE IN TREATING MEDICAL CONDITIONS | Ikena Oncology, Inc. (US) | 2024-03-28 | — | — | WO | disclosed |