Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 7/20 | 0.34 |
| ▸ | BACE2 | Q9Y5Z0 | 7/20 | 0.34 |
| ▸ | CTSD | P07339 | 3/20 | 0.34 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.32 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.32 |
| ▸ | FEN1 | P39748 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30848627 | 0.80 | BTK (0.32) | — | |
| SCHEMBL30848700 | 0.80 | CYP3A4 (0.47) | ALOX5APFEN1 | |
| SCHEMBL31310383 | 0.79 | LRRK2 (0.43) | LRRK2 | |
| SCHEMBL30326383 | 0.79 | CYP3A4 (0.37) | BACE1LRRK2ALOX5APFEN1 | |
| SCHEMBL30326372 | 0.79 | CYP3A4 (0.37) | BACE1LRRK2ALOX5APFEN1 | |
| SCHEMBL29265928 | 0.79 | CYP3A4 (0.37) | BACE1LRRK2ALOX5APFEN1 | |
| SCHEMBL29265903 | 0.71 | LRRK2 (0.37) | LRRK2 | |
| SCHEMBL30326712 | 0.71 | LRRK2 (0.37) | LRRK2 | |
| SCHEMBL29265829 | 0.69 | EGFR (0.41) | — | |
| SCHEMBL30326640 | 0.66 | DYRK1A (0.40) | LRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118043327-A | FGFR inhibitors and methods of use thereof | 思康睿奇(上海)药业有限公司 | 2024-05-14 | — | — | CN | disclosed |