Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.47 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.47 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | ALOX5AP | P20292 | 12/20 | 0.41 |
| ▸ | FEN1 | P39748 | 11/20 | 0.41 |
| ▸ | MAP2K1 | Q02750 | 6/20 | 0.31 |
| ▸ | RAF1 | P04049 | 5/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30848600 | 0.86 | CYP3A4 (0.36) | CYP3A4CYP2D6FGFR1CYP2C9FGFR2 | |
| SCHEMBL30848627 | 0.85 | BTK (0.32) | CYP3A4CYP2D6FGFR1CYP2C9FGFR2 | |
| SCHEMBL30848558 | 0.85 | CYP3A4 (0.35) | CYP3A4CYP2D6FGFR1CYP2C9FGFR2 | |
| SCHEMBL30325866 | 0.84 | CYP3A4 (0.64) | CYP3A4CYP2D6FGFR1CYP2C9FGFR2 | |
| SCHEMBL30325974 | 0.81 | CYP3A4 (0.58) | CYP3A4CYP2D6FGFR1CYP2C9FGFR2 | |
| SCHEMBL30325861 | 0.81 | FGFR1 (0.63) | CYP3A4CYP2D6FGFR1CYP2C9FGFR2 | |
| SCHEMBL30325667 | 0.81 | CYP3A4 (0.64) | CYP3A4CYP2D6FGFR1CYP2C9FGFR2 | |
| SCHEMBL30325943 | 0.81 | CYP3A4 (0.57) | CYP3A4CYP2D6FGFR1CYP2C9FGFR2 | |
| SCHEMBL30367018 | 0.81 | CYP3A4 (0.46) | CYP3A4CYP2D6FGFR1CYP2C9FGFR2 | |
| SCHEMBL31213850 | 0.80 | FGFR1 (0.73) | CYP3A4CYP2D6FGFR1CYP2C9FGFR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118043327-A | FGFR inhibitors and methods of use thereof | 思康睿奇(上海)药业有限公司 | 2024-05-14 | — | — | CN | disclosed |