Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.31 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.31 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30848600 | 0.85 | CYP3A4 (0.36) | BTKCYP3A4CYP2D6FGFR1CYP2C9 | |
| SCHEMBL30848700 | 0.85 | CYP3A4 (0.47) | CYP3A4CYP2D6FGFR1CYP2C9FGFR2 | |
| SCHEMBL30848558 | 0.84 | CYP3A4 (0.35) | BTKCYP3A4CYP2D6FGFR1CYP2C9 | |
| SCHEMBL30326056 | 0.83 | CYP3A4 (0.44) | BTKCYP3A4CYP2D6FGFR1CYP2C9 | |
| SCHEMBL30325940 | 0.83 | BTK (0.36) | BTKCYP3A4CYP2D6FGFR1CYP2C9 | |
| SCHEMBL30326114 | 0.82 | CYP3A4 (0.39) | BTKCYP3A4CYP2D6FGFR1CYP2C9 | |
| SCHEMBL30325786 | 0.80 | BTK (0.36) | BTKCYP3A4CYP2D6FGFR1CYP2C9 | |
| SCHEMBL30325679 | 0.80 | CYP3A4 (0.44) | CYP3A4CYP2D6FGFR1CYP2C9FGFR2 | |
| SCHEMBL30848568 | 0.80 | BACE1 (0.34) | — | |
| SCHEMBL30325953 | 0.80 | BTK (0.35) | BTKCYP3A4CYP2D6FGFR1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118043327-A | FGFR inhibitors and methods of use thereof | 思康睿奇(上海)药业有限公司 | 2024-05-14 | — | — | CN | disclosed |