Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL392679 | 1.00 | LMNA (0.51) | LMNAMEN1KMT2AHTTTSHR | |
| SCHEMBL14684937 | 0.87 | LMNA (0.43) | LMNAMEN1KMT2AHTTMAPT | |
| SCHEMBL30224794 | 0.87 | AKR1C3 (0.41) | LMNAMEN1KMT2AHTTTSHR | |
| SCHEMBL7425083 | 0.86 | ALDH1A1 (0.57) | LMNAMEN1KMT2AHTTTSHR | |
| SCHEMBL5201986 | 0.84 | LMNA (0.49) | LMNAMEN1KMT2AHTTMAPT | |
| SCHEMBL1694828 | 0.84 | MAPT (0.49) | LMNAMEN1KMT2AHTTTSHR | |
| SCHEMBL5092015 | 0.84 | LMNA (0.49) | LMNAMEN1KMT2AHTTMAPT | |
| SCHEMBL31085600 | 0.83 | LMNA (0.53) | LMNAMEN1KMT2AHTTMAPT | |
| SCHEMBL31085599 | 0.83 | LMNA (0.53) | LMNAMEN1KMT2AHTTMAPT | |
| SCHEMBL15270721 | 0.83 | LMNA (0.53) | LMNAMEN1KMT2AHTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118847245-A | Synthesis method of bromoalkyl substituted quinoxaline | 烟台宁远药业有限公司 | 2024-10-29 | — | — | CN | claimed |
| CN-118847245-A | Synthesis method of bromoalkyl substituted quinoxaline | 烟台宁远药业有限公司 | 2024-10-29 | — | — | CN | disclosed |
| CN-117794917-A | Novel indole derivatives, pharmaceutical compositions containing the same and uses thereof | 水疗免疫疗法有限公司 | 2024-03-29 | — | — | CN | disclosed |