Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 2/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.36 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 4/20 | 0.34 |
| ▸ | DRD2 | P14416 | 4/20 | 0.34 |
| ▸ | HTR7 | P34969 | 4/20 | 0.34 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.34 |
| ▸ | TUBB | P07437 | 3/20 | 0.34 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.34 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.34 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.34 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.34 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.34 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.34 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.34 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.34 |
| ▸ | TUBA1A | Q71U36 | 3/20 | 0.34 |
| ▸ | TUBA1C | Q9BQE3 | 3/20 | 0.34 |
| ▸ | TUBB6 | Q9BUF5 | 3/20 | 0.34 |
| ▸ | TUBB2B | Q9BVA1 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16798271 | 0.83 | FNTA (0.39) | CHRM4DRD2HTR7OPRK1 | |
| SCHEMBL3718804 | 0.83 | CHRM4 (0.34) | CHRM4DRD2HTR7TUBB4ATUBB | |
| SCHEMBL568592 | 0.83 | FNTA (0.37) | KDM5AKDM4CKDM5BCHRM4DRD2 | |
| SCHEMBL6643123 | 0.76 | CHRM4 (0.36) | KDM5AKDM4CKDM5BCHRM4DRD2 | |
| SCHEMBL10286452 | 0.75 | FNTA (0.38) | CHRM4DRD2HTR7OPRK1 | |
| SCHEMBL2147574 | 0.75 | DGAT1 (0.35) | CHRM4DRD2HTR7USP2CYP3A4 | |
| SCHEMBL2147611 | 0.75 | CHRM4 (0.41) | CHRM4DRD2HTR7 | |
| SCHEMBL10286869 | 0.74 | CHRM4 (0.35) | CHRM4DRD2HTR7OPRK1USP2 | |
| SCHEMBL30849375 | 0.72 | EPAS1 (0.40) | — | |
| SCHEMBL30849377 | 0.72 | EPAS1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117800949-A | Pyrimidine-containing polycyclic derivative, preparation method and application thereof | 江苏豪森药业集团有限公司 | 2024-04-02 | — | — | CN | disclosed |