Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.33 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.31 |
| ▸ | DPYD | Q12882 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1799199 | 0.82 | RPS6KA5 (0.42) | LRRK2AAK1RPS6KA5DPYD | |
| SCHEMBL25839045 | 0.66 | AAK1 (0.38) | LRRK2AAK1DPYD | |
| SCHEMBL5522171 | 0.64 | LRRK2 (0.40) | LRRK2DPYD | |
| SCHEMBL5260963 | 0.64 | LRRK2 (0.54) | LRRK2AAK1RPS6KA5 | |
| SCHEMBL30199352 | 0.64 | LRRK2 (0.54) | LRRK2AAK1RPS6KA5 | |
| SCHEMBL9254230 | 0.63 | JAK3 (0.39) | LRRK2DPYD | |
| SCHEMBL1737697 | 0.63 | CHEK1 (0.56) | LRRK2DPYD | |
| Hydrochloric Acid SCHEMBL28274256 | 0.63 | LRRK2 (0.53) | LRRK2AAK1RPS6KA5 | |
| SCHEMBL30849544 | 0.63 | CDK8 (0.53) | RPS6KA5 | |
| Purine SCHEMBL30151982 | 0.58 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117460736-A | Nucleoside derivatives having multi-target phosphorylase inhibitory activity and pharmaceutical compositions for preventing and treating cancer comprising the same | 未来制药有限公司 | 2024-01-26 | — | — | CN | disclosed |