SCHEMBL30849685

SCHEMBL30849685

COc1cccc(CC[C@@H](O)c2ccccc2)c1

nearest known ligand 0.53

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 1/20 0.53
ABCB1 P08183 3/20 0.51
HTR1A P08908 2/20 0.51
DRD2 P14416 2/20 0.51
CASR P41180 1/20 0.50
CHRM2 P08172 1/20 0.50
CHRM1 P11229 1/20 0.50
CHRM3 P20309 1/20 0.50
AOC3 Q16853 2/20 0.49
CYP2D6 P10635 2/20 0.48
HTR2A P28223 2/20 0.48
ABCG2 Q9UNQ0 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7710830 1.00 TAAR1 (0.53) TAAR1ABCB1HTR1ADRD2CASR
SCHEMBL21002046 0.92 AOC3 (0.57) TAAR1CASRCHRM2CHRM1CHRM3
SCHEMBL7169569 0.91 AOC3 (0.56) CASRCHRM2CHRM1CHRM3AOC3
SCHEMBL7713131 0.85 TAAR1 (0.57) TAAR1ABCB1HTR1ADRD2CASR
SCHEMBL11819483 0.84 TAAR1 (0.49) TAAR1ABCB1HTR1ADRD2CASR
SCHEMBL10235922 0.83 ALDH1A1 (0.47) CYP2D6L3MBTL1
SCHEMBL5355730 0.83 ALDH1A1 (0.57) HTR1AAOC3
SCHEMBL14839516 0.83 TDP1 (0.60) HTR1ACASR
SCHEMBL5631116 0.83 ALDH1A1 (0.57) HTR1AAOC3
SCHEMBL10719053 0.82 ADRB2 (0.69) CHRM2CHRM1CHRM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117865776-A Method for directly converting aromatic alkyne into chiral alcohol by one-pot method 三峡大学 2024-04-12 CN disclosed