Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.43 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.43 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.42 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.42 |
| ▸ | GSK3A | P49840 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.42 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.42 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.41 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.40 |
| ▸ | SELE | P16581 | 1/20 | 0.40 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30849844 | 0.87 | KDM4E (0.43) | KDRCSNK2A1CSNK1DGSK3AGSK3B | |
| SCHEMBL828767 | 0.79 | CSNK2A2 (0.44) | CSNK2A2KDRCSNK2BCSNK2A1RPS6KB1 | |
| SCHEMBL30714296 | 0.78 | RPS6KB1 (0.45) | CSNK2A2KDRCSNK2BCSNK2A1RPS6KB1 | |
| SCHEMBL26110533 | 0.78 | RPS6KB1 (0.45) | CSNK2A2KDRCSNK2BCSNK2A1RPS6KB1 | |
| SCHEMBL9431415 | 0.78 | RPS6KB1 (0.44) | CSNK2A2KDRCSNK2BCSNK2A1RPS6KB1 | |
| SCHEMBL3822544 | 0.75 | ICAM1 (0.41) | CSNK2A2KDRCSNK2BCSNK2A1RPS6KB1 | |
| SCHEMBL829006 | 0.75 | CSNK2A2 (0.46) | CSNK2A2KDRCSNK2BCSNK2A1RPS6KB1 | |
| SCHEMBL828902 | 0.74 | CSNK2A2 (0.48) | CSNK2A2KDRCSNK2BCSNK2A1RPS6KB1 | |
| SCHEMBL29207321 | 0.73 | — | — | |
| SCHEMBL15203667 | 0.73 | CSNK2A2 (0.49) | CSNK2A2KDRCSNK2BCSNK2A1RPS6KB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117800975-A | Compounds with anti-KRAS mutant tumor activity | 泰励生物科技（上海）有限公司 | 2024-04-02 | — | — | CN | disclosed |