Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | DAO | P14920 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | GPR35 | Q9HC97 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.37 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.37 |
| ▸ | PLK4 | O00444 | 2/20 | 0.36 |
| ▸ | AURKA | O14965 | 2/20 | 0.36 |
| ▸ | DAPK3 | O43293 | 2/20 | 0.36 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.36 |
| ▸ | CDK1 | P06493 | 2/20 | 0.36 |
| ▸ | PIM1 | P11309 | 2/20 | 0.36 |
| ▸ | CDK2 | P24941 | 2/20 | 0.36 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.36 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30849722 | 0.87 | CSNK2A2 (0.43) | KDM4EMAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL20022331 | 0.81 | DAO (0.46) | KDM4EDAOMAPTMEN1ALDH1A1 | |
| SCHEMBL30640499 | 0.78 | KDM4E (0.46) | KDM4EDAOMAPTMEN1ALDH1A1 | |
| SCHEMBL21505451 | 0.78 | KDM4E (0.46) | KDM4EDAOMAPTMEN1ALDH1A1 | |
| SCHEMBL25274256 | 0.75 | STING1 (0.53) | STING1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL26111219 | 0.74 | GPR35 (0.42) | DAOALDH1A1NOTUMGPR35PTPN2 | |
| SCHEMBL30714157 | 0.74 | GPR35 (0.42) | DAOALDH1A1NOTUMGPR35PTPN2 | |
| SCHEMBL29207321 | 0.74 | — | — | |
| SCHEMBL13737109 | 0.73 | GPR35 (0.46) | KDM4EDAOMAPTMEN1ALDH1A1 | |
| SCHEMBL20906130 | 0.72 | DAO (0.43) | KDM4EDAOMAPTMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117800975-A | Compounds with anti-KRAS mutant tumor activity | 泰励生物科技（上海）有限公司 | 2024-04-02 | — | — | CN | disclosed |