Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ICAM1 | P05362 | 1/20 | 0.41 |
| ▸ | SELE | P16581 | 1/20 | 0.41 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.41 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.41 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.41 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | PFKFB3 | Q16875 | 2/20 | 0.40 |
| ▸ | PFKFB4 | Q16877 | 2/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL828767 | 0.94 | CSNK2A2 (0.44) | ICAM1SELEVCAM1CSNK2A2CSNK2B | |
| SCHEMBL829703 | 0.92 | CSNK2A2 (0.47) | ICAM1SELEVCAM1CSNK2A2CSNK2B | |
| SCHEMBL21505451 | 0.81 | KDM4E (0.46) | ICAM1SELEVCAM1CSNK2A1HDAC1 | |
| SCHEMBL30640499 | 0.81 | KDM4E (0.46) | ICAM1SELEVCAM1CSNK2A1HDAC1 | |
| SCHEMBL26622003 | 0.81 | PTPN2 (0.45) | ICAM1SELEHDAC1HDAC3HDAC4 | |
| SCHEMBL24858604 | 0.79 | CCNC (0.46) | ICAM1SELEVCAM1CSNK2A2CSNK2B | |
| SCHEMBL26110533 | 0.79 | RPS6KB1 (0.45) | ICAM1SELEVCAM1CSNK2A2CSNK2B | |
| SCHEMBL9431710 | 0.79 | HDAC1 (0.52) | ICAM1SELEVCAM1CSNK2A2CSNK2B | |
| SCHEMBL30714296 | 0.79 | RPS6KB1 (0.45) | ICAM1SELEVCAM1CSNK2A2CSNK2B | |
| SCHEMBL829477 | 0.79 | CCNC (0.48) | ICAM1SELEVCAM1CSNK2A2CSNK2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1831192-A4 | BENZOTHIOPHEN-2-CARBONYLGUANIDINE DERIVATIVES, PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | KOREA RES INST CHEM TECH (KR) | 2009-08-19 | — | — | EP | disclosed |
| EP-1831192-A1 | BENZOTHIOPHEN-2-CARBONYLGUANIDINE DERIVATIVES, PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | Korea Research Institute of Chemical Technology (KR) | 2007-09-12 | — | — | EP | disclosed |
| WO-2006071047-A1 | BENZOTHIOPHEN-2-CARBONYLGUANIDINE DERIVATIVES, PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2006-07-06 | — | — | WO | disclosed |