SCHEMBL30850464

SCHEMBL30850464

CCOC(=O)c1cccc(-c2cc(Cl)ccc2OCCBr)c1

nearest known ligand 0.49

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
EIF4EBP1 Q13541 11/20 0.48
CYP2C9 P11712 1/20 0.47
PTGER1 P34995 1/20 0.47
PTGDR2 Q9Y5Y4 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29214612 0.86 EIF4EBP1 (0.47) EIF4EBP1CYP2C9PTGER1PTGDR2
SCHEMBL30891724 0.86 EIF4EBP1 (0.47) EIF4EBP1CYP2C9PTGER1PTGDR2
SCHEMBL5096044 0.81 PTGER1 (0.62) EIF4EBP1CYP2C9PTGER1
SCHEMBL5096241 0.81 PTGER1 (0.54) EIF4EBP1CYP2C9PTGER1
SCHEMBL16574049 0.81 TRPV1 (0.50)
SCHEMBL14028965 0.79 PTGER1 (0.60) EIF4EBP1CYP2C9PTGER1
SCHEMBL14029163 0.79 PTGER1 (0.60) EIF4EBP1CYP2C9PTGER1
SCHEMBL5099258 0.79 PTGER1 (0.77) CYP2C9PTGER1
SCHEMBL13871664 0.78 SUCNR1 (0.53)
SCHEMBL14028869 0.78 PTGER1 (0.59) EIF4EBP1CYP2C9PTGER1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4615848-A1 COMPOUNDS AND COMPOSITIONS AS EIF4E INHIBITORS AND USES THEREOF Ribometrix, Inc. (US) 2025-09-17 EP disclosed
US-20240246918-A1 COMPOUNDS AND COMPOSITIONS AS EIF4E INHIBITORS AND THE USES THEREOF RIBOMETRIX, INC. 2024-07-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240246918-A1 COMPOUNDS AND COMPOSITIONS AS EIF4E INHIBITORS AND THE USES THEREOF EIF4E, EIF4EBP1, EIF4A1 EIF4EBP1 2/4885CYP2C9 4047/4885PTGER1 3948/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.