Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EIF4EBP1 | Q13541 | 16/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.46 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.44 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29214612 | 1.00 | EIF4EBP1 (0.47) | EIF4EBP1CYP2C9PTGER1PTGDR2SLC6A9 | |
| SCHEMBL22866924 | 0.86 | EIF4EBP1 (0.45) | EIF4EBP1CYP2C9PTGER1PTGDR2SLC6A9 | |
| SCHEMBL29661889 | 0.86 | EIF4EBP1 (0.45) | EIF4EBP1CYP2C9PTGER1PTGDR2SLC6A9 | |
| SCHEMBL30850464 | 0.86 | EIF4EBP1 (0.48) | EIF4EBP1CYP2C9PTGER1PTGDR2 | |
| SCHEMBL22866872 | 0.81 | SLC6A9 (0.43) | EIF4EBP1CYP2C9PTGER1SLC6A9 | |
| SCHEMBL22866930 | 0.79 | SLC7A5 (0.41) | CYP2C9PTGER1 | |
| SCHEMBL29560131 | 0.75 | XPO1 (0.41) | SLC6A9 | |
| SCHEMBL12147621 | 0.74 | PTGDR2 (0.48) | EIF4EBP1CYP2C9PTGER1PTGDR2SLC6A9 | |
| SCHEMBL11617727 | 0.74 | PTGDR2 (0.61) | EIF4EBP1CYP2C9PTGER1PTGDR2SLC6A9 | |
| SCHEMBL22866680 | 0.74 | EIF4EBP1 (0.40) | EIF4EBP1CYP2C9PTGER1PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114269756-B | 4-Oxo-3, 4-dihydropyrido [3,4-D ] pyrimidine compounds that inhibit EIF4E | 效应疗法股份有限公司 | 2024-05-14 | — | — | CN | disclosed |