Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 8/20 | 0.60 |
| ▸ | AURKA | O14965 | 2/20 | 0.55 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.55 |
| ▸ | CLK4 | Q9HAZ1 | 8/20 | 0.53 |
| ▸ | EGFR | P00533 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 6/20 | 0.50 |
| ▸ | TSHR | P16473 | 6/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.50 |
| ▸ | CDC7 | O00311 | 1/20 | 0.48 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.48 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.48 |
| ▸ | JAK2 | O60674 | 1/20 | 0.48 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.48 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.48 |
| ▸ | PAK4 | O96013 | 1/20 | 0.48 |
| ▸ | ABL1 | P00519 | 1/20 | 0.48 |
| ▸ | LCK | P06239 | 1/20 | 0.48 |
| ▸ | CSF1R | P07333 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4921700 | 1.00 | CYP1A2 (0.60) | CYP1A2AURKARPS6KB1CLK4EGFR | |
| SCHEMBL20119574 | 0.87 | POLB (0.47) | CYP1A2AURKARPS6KB1CYP2C19TSHR | |
| SCHEMBL2623140 | 0.86 | RPS6KB1 (0.48) | CYP1A2AURKARPS6KB1CLK4EGFR | |
| SCHEMBL4920209 | 0.85 | AURKA (0.54) | CYP1A2AURKARPS6KB1CLK4EGFR | |
| SCHEMBL639807 | 0.84 | CDC7 (0.67) | AURKACLK4EGFRCDC7DBF4 | |
| SCHEMBL4923417 | 0.84 | EGFR (0.55) | CYP1A2AURKARPS6KB1CLK4EGFR | |
| SCHEMBL638499 | 0.84 | CCNB2 (0.59) | CYP1A2AURKARPS6KB1CLK4EGFR | |
| SCHEMBL4921713 | 0.84 | CDC7 (0.48) | CYP1A2AURKACLK4CYP2D6TSHR | |
| SCHEMBL30605167 | 0.84 | CCNB2 (0.59) | CYP1A2AURKARPS6KB1CLK4EGFR | |
| SCHEMBL621253 | 0.84 | CLK4 (0.67) | AURKARPS6KB1CLK4EGFRCDC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240116975-A1 | ADENOSINE A3 RECEPTOR AGONISTS, PREPARATION METHODS AND USES THEREOF | ZHEJIANG VIMGREEN PHARMACEUTICALS, LTD. (CN) | 2024-04-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240116975-A1 | ADENOSINE A3 RECEPTOR AGONISTS, PREPARATION METHODS AND USES THEREOF | ADORA3, ADORA2A, ADORA2B | CYP1A2 825/4885AURKA 2534/4885RPS6KB1 1321/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.