Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.69 |
| ▸ | NPC1 | O15118 | 8/20 | 0.69 |
| ▸ | RAB9A | P51151 | 8/20 | 0.69 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.69 |
| ▸ | TP53 | P04637 | 6/20 | 0.69 |
| ▸ | MAPT | P10636 | 3/20 | 0.69 |
| ▸ | GFER | P55789 | 1/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.63 |
| ▸ | HPGD | P15428 | 7/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.59 |
| ▸ | CASP3 | P42574 | 2/20 | 0.59 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.59 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.59 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.59 |
| ▸ | NFKB1 | P19838 | 5/20 | 0.52 |
| ▸ | NFKB2 | Q00653 | 5/20 | 0.52 |
| ▸ | RELA | Q04206 | 5/20 | 0.52 |
| ▸ | MAOA | P21397 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2245749 | 1.00 | KDM4E (0.69) | KDM4ENPC1RAB9AHSD17B10TP53 | |
| SCHEMBL25027923 | 0.84 | KDM4E (0.71) | KDM4ENPC1RAB9AHSD17B10TP53 | |
| SCHEMBL26745312 | 0.83 | KDM4E (0.70) | KDM4ENPC1RAB9AHSD17B10TP53 | |
| SCHEMBL28822907 | 0.81 | MAPT (0.64) | KDM4ENPC1RAB9AHSD17B10TP53 | |
| SCHEMBL27535586 | 0.81 | NPC1 (0.64) | KDM4ENPC1RAB9AHSD17B10TP53 | |
| SCHEMBL30129338 | 0.81 | KDM4E (0.64) | KDM4ENPC1RAB9AHSD17B10TP53 | |
| SCHEMBL3630700 | 0.81 | KDM4E (0.64) | KDM4ENPC1RAB9AHSD17B10TP53 | |
| SCHEMBL28823008 | 0.81 | MAPT (0.64) | KDM4ENPC1RAB9AHSD17B10TP53 | |
| SCHEMBL31344144 | 0.81 | MAPT (0.64) | KDM4ENPC1RAB9AHSD17B10TP53 | |
| SCHEMBL31239357 | 0.81 | KDM4E (0.65) | KDM4ENPC1RAB9AHSD17B10TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4744462-A1 | COMPOSITION | Merck Patent GmbH (DE) | 2026-05-20 | — | — | EP | disclosed |
| EP-4605438-A1 | COMPOSITION | Merck Patent GmbH (DE) | 2025-08-27 | — | — | EP | disclosed |
| WO-2025012183-A1 | COMPOSITION | MERCK PATENT GMBH (DE) | 2025-01-16 | — | — | WO | disclosed |
| WO-2024083874-A1 | COMPOSITION | MERCK PATENT GMBH (DE) | 2024-04-25 | — | — | WO | disclosed |