SCHEMBL30851365

SCHEMBL30851365

O=C1N=CC=C2C1=Cc1cccnc12

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP2 O95551 2/20 0.36
NSD2 O96028 2/20 0.36
PAX8 Q06710 2/20 0.36
TDP1 Q9NUW8 2/20 0.36
ABL1 P00519 1/20 0.36
PLCG1 P19174 1/20 0.36
CES1 P23141 1/20 0.36
RIN1 Q13671 1/20 0.36
MEN1 O00255 1/20 0.36
THRB P10828 1/20 0.36
BLM P54132 1/20 0.36
KMT2A Q03164 1/20 0.36
GAA P10253 1/20 0.36
S100A4 P26447 3/20 0.33
CDC25B P30305 3/20 0.33
PTPRC P08575 2/20 0.33
CTSL P07711 1/20 0.33
CTSS P25774 1/20 0.33
PTPN13 Q12923 1/20 0.33
TGM2 P21980 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7786853 0.71 CDC25B (0.39) TDP2PLCG1CES1MEN1THRB
SCHEMBL30851403 0.67 S100A4 (0.39) TDP2NSD2PAX8TDP1ABL1
SCHEMBL28494770 0.66 POLB (0.33) TDP1KDM4E
SCHEMBL25251959 0.66 TDP2 (0.39) TDP2NSD2PAX8TDP1ABL1
SCHEMBL30083032 0.65 TDP2 (0.45) TDP2NSD2PAX8TDP1ABL1
SCHEMBL24981816 0.65 TDP2 (0.45) TDP2NSD2PAX8TDP1ABL1
SCHEMBL31410969 0.65 PTPRC (0.42) TDP2NSD2PAX8TDP1ABL1
SCHEMBL28303186 0.63 TDP2 (0.43) TDP2NSD2PAX8TDP1ABL1
SCHEMBL1335811 0.62 S100A4 (0.40) TDP2NSD2PAX8TDP1ABL1
SCHEMBL29725127 0.62 S100A4 (0.40) TDP2NSD2PAX8TDP1ABL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112513014-B Light stabilizer compounds, compositions and methods ELC 管理有限责任公司 2024-01-30 CN disclosed