Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 4/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 4/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31068654 | 0.74 | ACACB (0.32) | HCRTR1HCRTR2 | |
| SCHEMBL11437617 | 0.74 | SMN1; SMN2 (0.43) | ALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL30852201 | 0.73 | ALDH1A1 (0.34) | ALDH1A1L3MBTL1HCRTR1HCRTR2 | |
| SCHEMBL29606513 | 0.73 | ALDH1A1 (0.40) | ALDH1A1L3MBTL1 | |
| SCHEMBL15633445 | 0.73 | ALDH1A1 (0.40) | ALDH1A1L3MBTL1 | |
| SCHEMBL18952506 | 0.72 | PDE8A (0.31) | — | |
| SCHEMBL30852237 | 0.72 | EDNRA (0.33) | — | |
| SCHEMBL5903240 | 0.68 | ALDH1A1 (0.52) | ALDH1A1L3MBTL1 | |
| SCHEMBL18970935 | 0.65 | — | — | |
| SCHEMBL15669873 | 0.65 | PIK3R1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4587014-A2 | C5AR1 ANTAGONISTS AND USES THEREOF | Vanqua Bio, Inc. (US) | 2025-07-23 | — | — | EP | disclosed |
| WO-2024059096-A2 | C5AR1 ANTAGONISTS AND USES THEREOF | VANQUA BIO, INC. (US) | 2024-03-21 | — | — | WO | disclosed |