Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | G6PD | P11413 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 6/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 6/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27314157 | 0.81 | ADORA2A (0.35) | ALDH1A1L3MBTL1MAPTKDM4EMEN1 | |
| SCHEMBL30851767 | 0.81 | ADORA2A (0.35) | ALDH1A1L3MBTL1MAPTKDM4EMEN1 | |
| Hydrochloric Acid SCHEMBL16446694 | 0.79 | ALDH1A1 (0.36) | ALDH1A1L3MBTL1MAPTKDM4EMEN1 | |
| SCHEMBL11437617 | 0.74 | SMN1; SMN2 (0.43) | ALDH1A1L3MBTL1MAPTMEN1KMT2A | |
| SCHEMBL31068646 | 0.74 | MAPT (0.41) | ALDH1A1L3MBTL1MAPTKDM4EMEN1 | |
| SCHEMBL30852001 | 0.73 | ALDH1A1 (0.34) | ALDH1A1L3MBTL1HCRTR1HCRTR2 | |
| SCHEMBL30851832 | 0.73 | ALDH1A1 (0.47) | ALDH1A1L3MBTL1MAPTKDM4EMEN1 | |
| SCHEMBL29606513 | 0.73 | ALDH1A1 (0.40) | ALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL15633445 | 0.73 | ALDH1A1 (0.40) | ALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL28080959 | 0.72 | SSTR4 (0.40) | ALDH1A1L3MBTL1MAPTKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4587014-A2 | C5AR1 ANTAGONISTS AND USES THEREOF | Vanqua Bio, Inc. (US) | 2025-07-23 | — | — | EP | disclosed |
| WO-2024059096-A2 | C5AR1 ANTAGONISTS AND USES THEREOF | VANQUA BIO, INC. (US) | 2024-03-21 | — | — | WO | disclosed |