Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | SSTR4 | P31391 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.34 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.33 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.33 |
| ▸ | WNT3A | P56704 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL803061 | 0.85 | ALDH1A1 (0.53) | L3MBTL1ALDH1A1SSTR4HSD17B10PLCG1 | |
| SCHEMBL507101 | 0.85 | ALDH1A1 (0.53) | L3MBTL1ALDH1A1SSTR4NFE2L2ADORA2A | |
| Hydrochloric Acid SCHEMBL2305254 | 0.83 | ALDH1A1 (0.52) | L3MBTL1ALDH1A1SSTR4NFE2L2ADORA2A | |
| SCHEMBL23355763 | 0.83 | L3MBTL1 (0.52) | L3MBTL1ALDH1A1SSTR4HSD17B10PLCG1 | |
| SCHEMBL25911810 | 0.83 | SSTR4 (0.36) | L3MBTL1ALDH1A1SSTR4GAASLC22A12 | |
| SCHEMBL30852043 | 0.81 | SSTR4 (0.35) | L3MBTL1ALDH1A1SSTR4GAASLC22A12 | |
| SCHEMBL2085967 | 0.77 | ALDH1A1 (0.46) | L3MBTL1ALDH1A1HSD17B10CHRM2CHRM4 | |
| SCHEMBL2084210 | 0.74 | ALDH1A1 (0.46) | L3MBTL1ALDH1A1HSD17B10PLCG1GAA | |
| SCHEMBL2083430 | 0.74 | ALDH1A1 (0.42) | L3MBTL1ALDH1A1NPC1RAB9A | |
| SCHEMBL18963844 | 0.72 | SLC22A12 (0.37) | L3MBTL1GAASLC22A12NFE2L2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4587014-A2 | C5AR1 ANTAGONISTS AND USES THEREOF | Vanqua Bio, Inc. (US) | 2025-07-23 | — | — | EP | disclosed |
| WO-2024059096-A2 | C5AR1 ANTAGONISTS AND USES THEREOF | VANQUA BIO, INC. (US) | 2024-03-21 | — | — | WO | disclosed |