Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | CFTR | P13569 | 3/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.40 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.39 |
| ▸ | TUBB | P07437 | 1/20 | 0.39 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.39 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.39 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.39 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.39 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.39 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.39 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.39 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.39 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.39 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.39 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.39 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.39 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27313510 | 1.00 | NPSR1 (0.42) | NPSR1CFTRPIK3CAPIK3CDPIK3CG | |
| SCHEMBL28805826 | 0.84 | GAA (0.43) | NPSR1CFTRTUBB4ATUBBTUBA3C | |
| SCHEMBL24550855 | 0.83 | KDM4E (0.53) | NPSR1KDM4EMAPTALDH1A1HPGD | |
| SCHEMBL29722018 | 0.83 | KDM4E (0.53) | NPSR1KDM4EMAPTALDH1A1HPGD | |
| SCHEMBL3863388 | 0.81 | ATR (0.39) | PIK3CAPIK3CDPIK3CGKCNH2MAP4K4 | |
| SCHEMBL27976390 | 0.81 | P2RX7 (0.46) | PIK3CAPIK3CDPIK3CGATR | |
| SCHEMBL31214234 | 0.81 | NPSR1 (0.42) | NPSR1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL31214354 | 0.79 | NPSR1 (0.41) | NPSR1CFTRTUBB4ATUBBTUBA3C | |
| SCHEMBL7449256 | 0.79 | L3MBTL1 (0.41) | NPSR1CFTRPIK3CAPIK3CDPIK3CG | |
| SCHEMBL26128177 | 0.79 | CFTR (0.49) | NPSR1CFTRTUBB4ATUBBTUBA3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4587014-A2 | C5AR1 ANTAGONISTS AND USES THEREOF | Vanqua Bio, Inc. (US) | 2025-07-23 | — | — | EP | disclosed |
| WO-2024059096-A2 | C5AR1 ANTAGONISTS AND USES THEREOF | VANQUA BIO, INC. (US) | 2024-03-21 | — | — | WO | disclosed |