Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 4/20 | 0.34 |
| ▸ | CDK9 | P50750 | 4/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | JAK1 | P23458 | 1/20 | 0.31 |
| ▸ | TYK2 | P29597 | 1/20 | 0.31 |
| ▸ | JAK3 | P52333 | 1/20 | 0.31 |
| ▸ | PDE5A | O76074 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
| ▸ | MIF | P14174 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17731129 | 0.77 | CYP11B1 (0.33) | CCNT1CDK9NPC1ALDH1A1TSHR | |
| SCHEMBL30851813 | 0.77 | CCNT1 (0.34) | CCNT1CDK9NPC1ALDH1A1TSHR | |
| SCHEMBL30852138 | 0.75 | KDM4E (0.40) | CCNT1CDK9NPC1ALDH1A1TSHR | |
| SCHEMBL17318345 | 0.74 | ALDH1A1 (0.37) | CCNT1CDK9ALDH1A1RAB9AJAK2 | |
| SCHEMBL30851928 | 0.74 | CCNT1 (0.34) | CCNT1CDK9NPC1ALDH1A1TSHR | |
| SCHEMBL19899836 | 0.74 | CDK9 (0.45) | CCNT1CDK9CYP11B1CYP11B2JAK2 | |
| SCHEMBL30852194 | 0.74 | CDK9 (0.38) | CCNT1CDK9RAB9AIDO1CYP11B1 | |
| SCHEMBL15182066 | 0.74 | SMN1; SMN2 (0.49) | NPC1ALDH1A1TSHRRAB9ASMN1; SMN2 | |
| SCHEMBL30852068 | 0.73 | CYP11B1 (0.41) | CCNT1CDK9RAB9AIDO1CYP11B1 | |
| SCHEMBL25270376 | 0.73 | ESR2 (0.43) | NPC1ALDH1A1RAB9ASMN1; SMN2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4587014-A2 | C5AR1 ANTAGONISTS AND USES THEREOF | Vanqua Bio, Inc. (US) | 2025-07-23 | — | — | EP | disclosed |
| WO-2024059096-A2 | C5AR1 ANTAGONISTS AND USES THEREOF | VANQUA BIO, INC. (US) | 2024-03-21 | — | — | WO | disclosed |