Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 6/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 4/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13180172 | 0.81 | TDP1 (0.54) | MCL1TDP1MEN1KMT2AERAP1 | |
| SCHEMBL13494166 | 0.78 | GPR35 (0.41) | MEN1KMT2ALMNAPPARGNCOA2 | |
| SCHEMBL3085227 | 0.76 | MCL1 (0.59) | MCL1TDP1MEN1KMT2AERAP1 | |
| SCHEMBL31114272 | 0.71 | MAOB (0.37) | MEN1KMT2AKDM4EGLAGAA | |
| SCHEMBL12714431 | 0.67 | ESR1 (0.40) | — | |
| SCHEMBL12038347 | 0.67 | GLA (0.38) | TDP1MEN1KMT2ALMNAKDM4E | |
| SCHEMBL4136788 | 0.67 | CYP2A6 (0.42) | MCL1TDP1MEN1KMT2ALMNA | |
| SCHEMBL31357189 | 0.67 | MCL1 (1.00) | MCL1TDP1MEN1KMT2AERAP1 | |
| SCHEMBL2552748 | 0.67 | MCL1 (1.00) | MCL1TDP1MEN1KMT2AERAP1 | |
| SCHEMBL14680363 | 0.66 | SMN1; SMN2 (0.47) | KMT2AKDM4EGAAALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10401361-B2 | Intracellular organelle peptide targeted enzyme substrates | MARKER GENE TECHNOLOGIES, INC. (US) | 2019-09-03 | — | — | US | disclosed |
| US-20180120317-A1 | INTRACELLULAR ORGANELLE PEPTIDE TARGETED ENZYME SUBSTRATES | MARKER GENE TECHNOLOGIES, INC. | 2018-05-03 | — | — | US | disclosed |
| US-20180120317-A1 | INTRACELLULAR ORGANELLE PEPTIDE TARGETED ENZYME SUBSTRATES | MARKER GENE TECHNOLOGIES, INC. | 2018-05-03 | — | — | US | disclosed |
| US-9841426-B2 | Intracellular organelle peptide targeted enzyme substrates | MARKER GENE TECHNOLOGIES, INC (US) | 2017-12-12 | — | — | US | disclosed |
| US-9841426-B2 | Intracellular organelle peptide targeted enzyme substrates | MARKER GENE TECHNOLOGIES, INC (US) | 2017-12-12 | — | — | US | disclosed |
| US-20150219654-A1 | INTRACELLULAR ORGANELLE PEPTIDE TARGETED ENZYME SUBSTRATES | MARKER GENE TECHNOLOGIES, INC. | 2015-08-06 | — | — | US | disclosed |
| US-20150219654-A1 | INTRACELLULAR ORGANELLE PEPTIDE TARGETED ENZYME SUBSTRATES | MARKER GENE TECHNOLOGIES, INC. | 2015-08-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10401361-B2 | Intracellular organelle peptide targeted enzyme substrates | GLG1, GBA3, MIA3 | MCL1 3218/4885TDP1 1126/4885MEN1 3784/4885 |
| US-20180120317-A1 | INTRACELLULAR ORGANELLE PEPTIDE TARGETED ENZYME SUBSTRATES | GLG1, GBA3, MIA3 | MCL1 3218/4885TDP1 1126/4885MEN1 3784/4885 |
| US-20150219654-A1 | INTRACELLULAR ORGANELLE PEPTIDE TARGETED ENZYME SUBSTRATES | GLG1, GBA3, MIA3 | MCL1 3218/4885TDP1 1126/4885MEN1 3784/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.