SCHEMBL30852409

SCHEMBL30852409

COC(=O)C(CC(=O)c1ccccc1NC(C)=O)NC(C)=O

nearest known ligand 0.66

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.48
CYP2C19 P33261 3/20 0.48
KMT2A Q03164 3/20 0.48
HSD17B10 Q99714 2/20 0.48
CYP1A2 P05177 1/20 0.48
POLB P06746 1/20 0.47
ALDH1A1 P00352 6/20 0.46
LMNA P02545 2/20 0.46
HPGD P15428 4/20 0.45
TSHR P16473 1/20 0.44
MAPT P10636 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
CYP2C9 P11712 1/20 0.44
HTT P42858 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
RAB9A P51151 2/20 0.43
GAA P10253 1/20 0.43
STAT1 P42224 1/20 0.43
NPC1 O15118 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30852406 0.86 CYP2C19 (0.53) KDM4ECYP2C19KMT2AHSD17B10CYP1A2
SCHEMBL27372476 0.85 MAPT (0.47) KDM4ECYP2C19KMT2AHSD17B10CYP1A2
SCHEMBL30852329 0.85 MAPT (0.47) KDM4ECYP2C19KMT2AHSD17B10CYP1A2
SCHEMBL34461796 0.84 MAPK1 (0.48) KDM4ECYP2C19KMT2AHSD17B10CYP1A2
SCHEMBL27371789 0.83 LMNA (0.46) KDM4ECYP2C19KMT2AHSD17B10CYP1A2
SCHEMBL30852354 0.82 KDM4E (0.40) KDM4ECYP2C19KMT2AHSD17B10CYP1A2
SCHEMBL30852395 0.79 HSD17B10 (0.43) KDM4ECYP2C19KMT2AHSD17B10CYP1A2
SCHEMBL34461794 0.78 ALDH1A1 (0.43) KDM4ECYP2C19KMT2AHSD17B10CYP1A2
SCHEMBL31520086 0.78 ALDH1A1 (0.46) KDM4EKMT2AHSD17B10ALDH1A1LMNA
SCHEMBL8743245 0.75 TSHR (0.66) KDM4ECYP2C19KMT2AHSD17B10CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120019060-A Compounds and their use for filtering ultraviolet and/or high-energy visible light 索利奥美公司 2025-05-16 CN claimed
EP-4587007-A2 COMPOUNDS AND THEIR USE IN FILTERING ULTRAVIOLET AND/OR HIGH-ENERGY VISIBLE LIGHT Soliome, Inc. (US) 2025-07-23 EP disclosed
CN-120019060-A Compounds and their use for filtering ultraviolet and/or high-energy visible light 索利奥美公司 2025-05-16 CN disclosed
WO-2024059119-A2 COMPOUNDS AND THEIR USE IN FILTERING ULTRAVIOLET AND/OR HIGH-ENERGY VISIBLE LIGHT SOLIOME, INC. (US) 2024-03-21 WO disclosed