Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14238731 | 1.00 | ALDH1A1 (0.55) | ALDH1A1CYP1A2CYP2C9GAAMEN1 | |
| SCHEMBL18969713 | 0.82 | ALOX12 (0.36) | KMT2AALOX12POLBSMN1; SMN2 | |
| SCHEMBL14237953 | 0.81 | GAA (0.61) | ALDH1A1CYP1A2CYP2C9GAAMEN1 | |
| SCHEMBL29328606 | 0.81 | GAA (0.61) | ALDH1A1CYP1A2CYP2C9GAAMEN1 | |
| SCHEMBL14237937 | 0.81 | GAA (0.61) | ALDH1A1CYP1A2CYP2C9GAAMEN1 | |
| SCHEMBL29475719 | 0.81 | GAA (0.61) | ALDH1A1CYP1A2CYP2C9GAAMEN1 | |
| SCHEMBL14237747 | 0.81 | ALOX12 (0.48) | ALDH1A1CYP1A2CYP2C9GAAMEN1 | |
| SCHEMBL29034567 | 0.81 | GAA (0.47) | ALDH1A1CYP1A2CYP2C9GAAMEN1 | |
| SCHEMBL1562501 | 0.78 | ALDH1A1 (0.61) | ALDH1A1CYP1A2CYP2C9GAAMEN1 | |
| SCHEMBL23790724 | 0.77 | ALDH1A1 (0.52) | ALDH1A1CYP1A2CYP2C9GAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4598586-A1 | DRUG LINKERS AND ANTIBODY CONJUGATES THEREOF | Ambrx, Inc. (US) | 2025-08-13 | — | — | EP | disclosed |
| WO-2024077277-A1 | DRUG LINKERS AND ANTIBODY CONJUGATES THEREOF | AMBRX, INC. (US) | 2024-04-11 | — | — | WO | disclosed |