SCHEMBL30852861

SCHEMBL30852861

CC(C)(C)OC[C@H](NC(=O)[C@H](COC(C)(C)C)NC(=O)[C@@H]1CCCN1C(=O)CN)C(=O)NCC(N)=O

nearest known ligand 0.38

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 1/20 0.36
▸ OPRM1 P35372 1/20 0.35
▸ OPRD1 P41143 1/20 0.35
▸ OPRK1 P41145 1/20 0.35
▸ NAA50 Q9GZZ1 1/20 0.35
▸ F2 P00734 2/20 0.34
▸ REN P00797 1/20 0.34
▸ SMN1; SMN2 Q16637 1/20 0.34
▸ CAPN1 P07384 2/20 0.34
▸ F10 P00742 1/20 0.34
▸ PLG P00747 1/20 0.34
▸ PRSS1 P07477 1/20 0.34
▸ GRB2 P62993 1/20 0.34
▸ APLNR P35414 1/20 0.34
▸ CMA1 P23946 1/20 0.33
▸ PTPN1 P18031 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30028199 0.92 CMA1 (0.40) KMT2AOPRM1OPRD1OPRK1REN
SCHEMBL30028577 0.84 KMT2A (0.45) KMT2AF2SMN1; SMN2CMA1
SCHEMBL30543475 0.82 GRB2 (0.41) KMT2AOPRM1OPRD1CAPN1GRB2
SCHEMBL35211230 0.80 F2 (0.40) OPRM1OPRD1OPRK1F2CMA1
SCHEMBL31347336 0.78 CAPN1 (0.42) OPRM1OPRD1NAA50CAPN1APLNR
SCHEMBL30138992 0.77 CAPN1 (0.40) OPRM1OPRD1F2CAPN1
SCHEMBL30493192 0.77 ITGB1 (0.36) F2CMA1
SCHEMBL31501249 0.75 APLNR (0.41) OPRM1OPRD1OPRK1CAPN1GRB2
SCHEMBL31347345 0.75 CMA1 (0.37) KMT2AOPRM1OPRD1NAA50APLNR
SCHEMBL4258292 0.75 F2 (0.39) NAA50F2APLNRPTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260125423-A1 PEPTIDES FOR INCRETIN SYNTHESIS LILLY CO ELI (US) 2026-05-07 — — US disclosed
EP-4598938-A2 PEPTIDES FOR INCRETIN SYNTHESIS Eli Lilly and Company (US) 2025-08-13 — — EP disclosed
WO-2024077149-A2 PEPTIDES FOR INCRETIN SYNTHESIS ELI LILLY AND COMPANY (US) 2024-04-11 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260125423-A1 PEPTIDES FOR INCRETIN SYNTHESIS IAPP, GLP1R, VIP KMT2A 3022/4885OPRM1 3191/4885OPRD1 3775/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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