SCHEMBL4258292

SCHEMBL4258292

NCC(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(N)=O)C(=O)NCC(=O)O

nearest known ligand 0.45

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
F2 P00734 2/20 0.39
ITGB1 P05556 1/20 0.39
ITGA4 P13612 1/20 0.39
NTMT1 Q9BV86 2/20 0.39
AVPR1A P37288 3/20 0.37
AVPR2 P30518 2/20 0.37
OXTR P30559 2/20 0.37
AVPR1B P47901 2/20 0.37
APLNR P35414 1/20 0.37
ACE P12821 2/20 0.36
TBXA2R P21731 1/20 0.36
PDE4D Q08499 1/20 0.36
PDE3A Q14432 1/20 0.36
PTPN1 P18031 1/20 0.36
ITGB3 P05106 1/20 0.36
ITGA2B P08514 1/20 0.36
NAA50 Q9GZZ1 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31544467 0.92 APLNR (0.40) F2ITGB1ITGA4NTMT1APLNR
SCHEMBL28890650 0.92 APLNR (0.40) F2ITGB1ITGA4NTMT1APLNR
SCHEMBL4726314 0.92 APLNR (0.40) F2ITGB1ITGA4NTMT1APLNR
SCHEMBL4959057 0.92 ACE (0.40) F2NTMT1APLNRACENAA50
SCHEMBL4726312 0.92 APLNR (0.40) F2ITGB1ITGA4NTMT1APLNR
SCHEMBL31070022 0.91 APLNR (0.42) F2NTMT1APLNRNAA50
SCHEMBL30493192 0.89 ITGB1 (0.36) F2ITGB1ITGA4NTMT1AVPR1A
SCHEMBL29832781 0.89 APLNR (0.38) F2NTMT1APLNRPTPN1NAA50
SCHEMBL29816717 0.87 NTMT1 (0.50) F2ITGB1ITGA4NTMT1AVPR1A
SCHEMBL30563305 0.87 GRB2 (0.44) F2NTMT1ACEPTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12257323-B2 Modified wound dressings CONVATEC TECHNOLOGIES INC. (US) 2025-03-25 US disclosed
US-11992575-B2 Radioactive liquid embolic MICROVENTION, INC. (US) 2024-05-28 US disclosed
US-20240123091-A1 MODIFIED WOUND DRESSINGS CONVATEC TECHNOLOGIES, INC. 2024-04-18 US disclosed
US-11865192-B2 Modified wound dressings CONVATEC TECHNOLOGIES, INC. (US) 2024-01-09 US disclosed
EP-3436012-B1 MODIFIED WOUND DRESSINGS CONVATEC TECHNOLOGIES INC (US) 2023-09-20 EP disclosed
EP-4121130-A1 LIQUID EMBOLICS MicroVention, Inc. (US) 2023-01-25 EP disclosed
US-20090169652-A1 Personal Care Compositions THE PROCTER & GAMBLE COMPANY 2009-07-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240123091-A1 MODIFIED WOUND DRESSINGS MMP8, CD68, ELANE F2 1173/4885ITGB1 1241/4885ITGA4 1218/4885
US-20090169652-A1 Personal Care Compositions CUTA, C5, F7 F2 397/4885ITGB1 624/4885ITGA4 406/4885
US-11865192-B2 Modified wound dressings MMP8, CD68, ELANE F2 1173/4885ITGB1 1241/4885ITGA4 1218/4885
US-12257323-B2 Modified wound dressings MMP8, CD68, ELANE F2 1173/4885ITGB1 1241/4885ITGA4 1218/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.