Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 3/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MET | P08581 | 1/20 | 0.34 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24752408 | 1.00 | CHRNB2 (0.39) | CHRNB2CHRNA4MCHR1MEN1POLB | |
| SCHEMBL29189625 | 1.00 | CHRNB2 (0.39) | CHRNB2CHRNA4MCHR1MEN1POLB | |
| SCHEMBL27094511 | 0.81 | S1PR4 (0.38) | MCHR1MEN1POLBKMT2ASLC6A2 | |
| SCHEMBL27094512 | 0.81 | S1PR4 (0.38) | MCHR1MEN1POLBKMT2ASLC6A2 | |
| SCHEMBL3513772 | 0.78 | MEN1 (0.46) | CHRNB2CHRNA4MCHR1MEN1POLB | |
| SCHEMBL30454073 | 0.78 | MEN1 (0.46) | CHRNB2CHRNA4MCHR1MEN1POLB | |
| SCHEMBL20897941 | 0.77 | CHRNB2 (0.36) | CHRNB2CHRNA4LMNASMN1; SMN2 | |
| SCHEMBL20897947 | 0.77 | CHRNB2 (0.36) | CHRNB2CHRNA4LMNASMN1; SMN2 | |
| SCHEMBL16904329 | 0.75 | CHRNB2 (0.40) | CHRNB2CHRNA4MEN1POLBKMT2A | |
| SCHEMBL9700633 | 0.74 | MCHR1 (0.43) | MCHR1MEN1KMT2ASLC6A2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117881681-A | Substituted pyrrolo [2,3-d ] pyrimidines, their preparation and their therapeutic use | 赛诺菲 | 2024-04-12 | — | — | CN | disclosed |