Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | HPGD | P15428 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | MMP13 | P45452 | 7/20 | 0.53 |
| ▸ | MMP2 | P08253 | 5/20 | 0.53 |
| ▸ | MMP14 | P50281 | 3/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16505827 | 1.00 | RAB9A (0.54) | RAB9AKDM4EALDH1A1HPGDLMNA | |
| SCHEMBL832252 | 0.82 | KDM4E (0.58) | RAB9AKDM4EALDH1A1HPGDLMNA | |
| SCHEMBL30023186 | 0.79 | HSD17B10 (0.49) | KDM4EALDH1A1HPGDLMNASMN1; SMN2 | |
| SCHEMBL22411420 | 0.78 | CYP1A2 (0.50) | RAB9AKDM4EALDH1A1HPGDLMNA | |
| SCHEMBL30873871 | 0.78 | CYP1A2 (0.50) | RAB9AKDM4EALDH1A1HPGDLMNA | |
| SCHEMBL15367087 | 0.78 | KDM4E (0.63) | RAB9AKDM4EALDH1A1HPGDLMNA | |
| SCHEMBL16008122 | 0.76 | CDK1 (0.57) | RAB9AKDM4EALDH1A1HPGDLMNA | |
| SCHEMBL13064936 | 0.76 | ALDH1A1 (0.57) | RAB9AKDM4EALDH1A1HPGDLMNA | |
| SCHEMBL16505498 | 0.75 | CYP1A2 (0.49) | RAB9AKDM4EALDH1A1HPGDNPC1 | |
| SCHEMBL22428818 | 0.75 | PDE4A (0.52) | KDM4EALDH1A1HPGDSMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4524136-A1 | KINESIN KIF18A INHIBITOR AND USE THEREOF | Shanghai Apeiron Therapeutics Company Limited (CN) | 2025-03-19 | — | — | EP | disclosed |
| CN-119156382-A | Kinesin KIF18A inhibitor and application thereof | 上海湃隆生物科技有限公司 | 2024-12-17 | — | — | CN | disclosed |
| CN-115397822-B | CBP/EP300 inhibitors and uses thereof | 南京药石科技股份有限公司 | 2024-04-16 | — | — | CN | disclosed |