Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIP4K2A | P48426 | 4/20 | 0.43 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | AXL | P30530 | 1/20 | 0.39 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TTK | P33981 | 2/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | PDE5A | O76074 | 1/20 | 0.38 |
| ▸ | PDE1A | P54750 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30853528 | 0.92 | PIP4K2A (0.42) | PIP4K2APIK3CGLMNAMAPTMEN1 | |
| SCHEMBL30853524 | 0.87 | PIP4K2A (0.44) | PIP4K2APIK3CGLMNAMAPTKDM4E | |
| SCHEMBL30853523 | 0.84 | PIP4K2A (0.47) | PIP4K2APIK3CGLMNAMAPTKDM4E | |
| SCHEMBL30853519 | 0.84 | HSP90AA1 (0.43) | PIP4K2APIK3CGLMNAMAPTMEN1 | |
| SCHEMBL30853522 | 0.84 | FER (0.47) | PIP4K2APIK3CGLMNAMAPTMEN1 | |
| SCHEMBL30853544 | 0.82 | PIP4K2A (0.43) | PIP4K2APIK3CGLMNAMAPTHPGD | |
| SCHEMBL30853521 | 0.80 | CTSS (0.43) | PIP4K2APIK3CGTP53EGFR | |
| SCHEMBL30853538 | 0.79 | PRKCQ (0.44) | PIP4K2APIK3CGLMNA | |
| SCHEMBL30853535 | 0.77 | HSP90AA1 (0.51) | — | |
| SCHEMBL30853541 | 0.77 | PIP4K2A (0.44) | PIP4K2APIK3CGLMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118047781-A | HSP90 inhibitor and preparation method and application thereof | 广西大学 | 2024-05-17 | — | — | CN | disclosed |