Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNK | O75909 | 16/20 | 0.68 |
| ▸ | CDK12 | Q9NYV4 | 16/20 | 0.68 |
| ▸ | CCNT1 | O60563 | 13/20 | 0.68 |
| ▸ | CCNE1 | P24864 | 13/20 | 0.68 |
| ▸ | CDK2 | P24941 | 13/20 | 0.68 |
| ▸ | CDK9 | P50750 | 13/20 | 0.68 |
| ▸ | CDK7 | P50613 | 12/20 | 0.68 |
| ▸ | CCNH | P51946 | 12/20 | 0.68 |
| ▸ | MNAT1 | P51948 | 9/20 | 0.68 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.68 |
| ▸ | MAP2K5 | Q13163 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27162428 | 1.00 | CCNK (0.68) | CCNKCDK12CCNT1CCNE1CDK2 | |
| SCHEMBL24176442 | 0.92 | CCNK (0.63) | CCNKCDK12CCNT1CCNE1CDK2 | |
| SCHEMBL30771913 | 0.92 | CCNK (0.63) | CCNKCDK12CCNT1CCNE1CDK2 | |
| SCHEMBL29498458 | 0.91 | CCNK (0.69) | CCNKCDK12CCNT1CCNE1CDK2 | |
| SCHEMBL21184369 | 0.90 | CCNK (0.69) | CCNKCDK12CCNT1CCNE1CDK2 | |
| SCHEMBL21184374 | 0.88 | CCNK (0.78) | CCNKCDK12CCNT1CCNE1CDK2 | |
| SCHEMBL26327191 | 0.86 | CCNK (0.68) | CCNKCDK12CCNT1CCNE1CDK2 | |
| SCHEMBL29850496 | 0.86 | CCNK (0.71) | CCNKCDK12CCNT1CCNE1CDK2 | |
| SCHEMBL28817405 | 0.86 | CCNK (0.71) | CCNKCDK12CCNT1CCNE1CDK2 | |
| SCHEMBL28817406 | 0.86 | CCNK (0.71) | CCNKCDK12CCNT1CCNE1CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11918592-B2 | Inhibitors of cyclin dependent kinase 7 (CDK7) | SYROS PHARMACEUTICALS, INC. (US) | 2024-03-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11918592-B2 | Inhibitors of cyclin dependent kinase 7 (CDK7) | CDK7, CDK3, CCNK | CCNK 3/4885CDK12 27/4885CCNT1 35/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.