Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC40A1 | Q9NP59 | 15/20 | 0.72 |
| ▸ | NFKBIA | P25963 | 2/20 | 0.65 |
| ▸ | RELA | Q04206 | 2/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | MAPT | P10636 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | MITF | O75030 | 1/20 | 0.62 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.62 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.62 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | CKS1B | P61024 | 1/20 | 0.62 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.62 |
| ▸ | MMP2 | P08253 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29255667 | 1.00 | SLC40A1 (0.72) | SLC40A1NFKBIARELAKMT2ATDP1 | |
| SCHEMBL1507919 | 0.87 | SLC40A1 (0.76) | SLC40A1NFKBIARELAKMT2ATDP1 | |
| SCHEMBL30854809 | 0.87 | SLC40A1 (0.76) | SLC40A1NFKBIARELAKMT2ATDP1 | |
| SCHEMBL27214272 | 0.87 | SLC40A1 (0.68) | SLC40A1NFKBIARELAKMT2ATDP1 | |
| SCHEMBL30925572 | 0.87 | SLC40A1 (0.68) | SLC40A1NFKBIARELAKMT2ATDP1 | |
| SCHEMBL30925525 | 0.86 | SLC40A1 (0.80) | SLC40A1NFKBIARELAKMT2ATDP1 | |
| SCHEMBL27214283 | 0.86 | SLC40A1 (0.80) | SLC40A1NFKBIARELAKMT2ATDP1 | |
| SCHEMBL30925483 | 0.85 | SLC40A1 (0.68) | SLC40A1NFKBIARELAKMT2ATDP1 | |
| SCHEMBL27214213 | 0.85 | SLC40A1 (0.68) | SLC40A1NFKBIARELAKMT2ATDP1 | |
| SCHEMBL30925451 | 0.84 | SLC40A1 (1.00) | SLC40A1NFKBIARELAKMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117865886-B | N- (quinoline-8-yl) quinoline-8-sulfonamide compound and application thereof | 中国药科大学 | 2024-05-10 | — | — | CN | disclosed |
| CN-117865886-A | N- (quinoline-8-yl) quinoline-8-sulfonamide compound and application thereof | 中国药科大学 | 2024-04-12 | — | — | CN | disclosed |