Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN1A | P35498 | 1/20 | 0.48 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.48 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.48 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.38 |
| ▸ | QPCT | Q16769 | 1/20 | 0.38 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25251059 | 0.87 | SCN1A (0.59) | SCN1ASCN2ASCN3AQPCTSLC2A1 | |
| SCHEMBL30438903 | 0.87 | SCN1A (0.59) | SCN1ASCN2ASCN3AQPCTSLC2A1 | |
| SCHEMBL30245520 | 0.82 | ROCK2 (0.42) | ROCK2ROCK1KDM4EALDH1A1NR3C1 | |
| SCHEMBL25253423 | 0.82 | ROCK2 (0.42) | ROCK2ROCK1KDM4EALDH1A1NR3C1 | |
| SCHEMBL30245941 | 0.80 | KDM4E (0.46) | ROCK2ROCK1KDM4EALDH1A1NR3C1 | |
| SCHEMBL25292340 | 0.77 | KDM4E (0.51) | ROCK2ROCK1KDM4EALDH1A1QPCT | |
| SCHEMBL30854977 | 0.76 | ROCK2 (0.49) | ROCK2ROCK1KDM4EALDH1A1GAA | |
| SCHEMBL30854997 | 0.76 | PPARA (0.41) | ROCK2ROCK1KDM4EALDH1A1NR3C1 | |
| SCHEMBL25298161 | 0.75 | PPARA (0.41) | ROCK2ROCK1ALDH1A1QPCTTSHR | |
| SCHEMBL25251323 | 0.75 | PPARA (0.41) | ROCK2ROCK1ALDH1A1QPCTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117916237-A | Amino aryl integrin agonist compounds | 德克萨斯心脏研究所 | 2024-04-19 | — | — | CN | claimed |
| CN-117916237-A | Amino aryl integrin agonist compounds | 德克萨斯心脏研究所 | 2024-04-19 | — | — | CN | disclosed |