Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 2/20 | 0.49 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | AURKA | O14965 | 1/20 | 0.47 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30855010 | 0.87 | ALDH1A1 (0.55) | ALDH1A1KDM4EHPGDL3MBTL1GAA | |
| SCHEMBL13210757 | 0.77 | ALDH1A1 (0.49) | ALDH1A1KDM4EHPGDL3MBTL1GAA | |
| SCHEMBL25046109 | 0.76 | BCHE (0.58) | ALDH1A1KDM4EGAAAURKARPS6KB1 | |
| SCHEMBL30854960 | 0.76 | SCN1A (0.48) | ROCK2ROCK1ALDH1A1KDM4EHPGD | |
| SCHEMBL22191536 | 0.75 | AURKA (0.49) | ROCK2ROCK1ALDH1A1KDM4EGAA | |
| SCHEMBL17790188 | 0.75 | KDM4E (0.51) | ROCK2ROCK1ALDH1A1KDM4EGAA | |
| SCHEMBL30855029 | 0.75 | AURKA (0.47) | ROCK2ROCK1ALDH1A1KDM4EGAA | |
| SCHEMBL3635025 | 0.73 | KDM4E (0.60) | KDM4EHPGDL3MBTL1GAAAURKA | |
| SCHEMBL259508 | 0.73 | LMNA (0.63) | KDM4EHPGDGAASMN1; SMN2LMNA | |
| SCHEMBL25302034 | 0.73 | CHRM2 (0.59) | ALDH1A1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117916237-A | Amino aryl integrin agonist compounds | 德克萨斯心脏研究所 | 2024-04-19 | — | — | CN | claimed |
| CN-117916237-A | Amino aryl integrin agonist compounds | 德克萨斯心脏研究所 | 2024-04-19 | — | — | CN | disclosed |