Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLOD2 | O00469 | 2/20 | 0.55 |
| ▸ | PLOD3 | O60568 | 2/20 | 0.55 |
| ▸ | PLOD1 | Q02809 | 2/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.54 |
| ▸ | TTBK1 | Q5TCY1 | 1/20 | 0.53 |
| ▸ | TTBK2 | Q6IQ55 | 1/20 | 0.53 |
| ▸ | PIM1 | P11309 | 1/20 | 0.52 |
| ▸ | PLK4 | O00444 | 2/20 | 0.50 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.50 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.50 |
| ▸ | CDK2 | P24941 | 1/20 | 0.50 |
| ▸ | CDK9 | P50750 | 1/20 | 0.50 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30854958 | 0.84 | MAPT (0.65) | TTBK1TTBK2PLK4MAPTKDM4E | |
| SCHEMBL6992776 | 0.79 | LMNA (0.57) | PLOD2PLOD3PLOD1HDAC3HDAC1 | |
| SCHEMBL30854948 | 0.78 | KDM4E (0.69) | PLOD2PLOD3PLOD1PLK4MAPT | |
| SCHEMBL30855009 | 0.78 | HDAC3 (0.53) | HDAC3HDAC1HDAC2HDAC6TTBK1 | |
| SCHEMBL2087362 | 0.78 | LMNA (0.55) | PLOD2PLOD3PLOD1HDAC3HDAC1 | |
| SCHEMBL31025693 | 0.77 | HDAC3 (0.49) | PLOD2PLOD3PLOD1HDAC3HDAC1 | |
| SCHEMBL25193121 | 0.77 | HDAC3 (0.52) | HDAC3HDAC1HDAC2HDAC6TTBK1 | |
| SCHEMBL19623431 | 0.76 | HDAC1 (0.56) | PLOD2PLOD3PLOD1HDAC3HDAC1 | |
| SCHEMBL27970512 | 0.76 | LMNA (0.53) | PLOD2PLOD3PLOD1HDAC3HDAC1 | |
| SCHEMBL108137 | 0.76 | LMNA (0.53) | PLOD2PLOD3PLOD1HDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117916237-A | Amino aryl integrin agonist compounds | 德克萨斯心脏研究所 | 2024-04-19 | — | — | CN | claimed |
| CN-117916237-A | Amino aryl integrin agonist compounds | 德克萨斯心脏研究所 | 2024-04-19 | — | — | CN | disclosed |