Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | TTBK1 | Q5TCY1 | 1/20 | 0.52 |
| ▸ | TTBK2 | Q6IQ55 | 1/20 | 0.52 |
| ▸ | PLK4 | O00444 | 2/20 | 0.52 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.51 |
| ▸ | JAK2 | O60674 | 5/20 | 0.49 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.49 |
| ▸ | CDK2 | P24941 | 2/20 | 0.49 |
| ▸ | CDK9 | P50750 | 2/20 | 0.49 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.49 |
| ▸ | PIM1 | P11309 | 1/20 | 0.48 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.46 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.45 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.45 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.45 |
| ▸ | JAK3 | P52333 | 2/20 | 0.44 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5200210 | 0.85 | PLK4 (0.53) | PLK4JAK2MAPK10 | |
| SCHEMBL30854979 | 0.79 | AGXT (0.49) | HDAC1PLK4CAMK2DNTRK1 | |
| SCHEMBL30854992 | 0.78 | PLOD2 (0.55) | HDAC3HDAC1HDAC2HDAC6TTBK1 | |
| SCHEMBL4463575 | 0.76 | PLK4 (0.69) | HDAC3HDAC1HDAC2HDAC6TTBK1 | |
| SCHEMBL20260113 | 0.75 | VCP (0.61) | HDAC3HDAC1HDAC2HDAC6TTBK1 | |
| SCHEMBL6992776 | 0.75 | LMNA (0.57) | HDAC3HDAC1HDAC2HDAC6TTBK1 | |
| SCHEMBL544111 | 0.74 | MEN1 (0.50) | CAMK2DCDK2 | |
| SCHEMBL2087362 | 0.74 | LMNA (0.55) | HDAC3HDAC1HDAC2HDAC6TTBK1 | |
| SCHEMBL5199413 | 0.73 | CD274 (0.46) | PLK4JAK2PIM1MAPK10NTRK1 | |
| SCHEMBL19623431 | 0.72 | HDAC1 (0.56) | HDAC3HDAC1HDAC2HDAC6TTBK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117916237-A | Amino aryl integrin agonist compounds | 德克萨斯心脏研究所 | 2024-04-19 | — | — | CN | claimed |
| CN-117916237-A | Amino aryl integrin agonist compounds | 德克萨斯心脏研究所 | 2024-04-19 | — | — | CN | disclosed |